Polycystic ovary syndrome, commonly shortened as PCOS, is an endocrine disorder that has a wide range of causes, all of which are still not understood completely in the medical world as we speak. Although the condition has been linked to a number of possible causes, it is by far and large believed to be a genetic disease.
According to the latest research findings, 5 out of every 10 women between the reproductive age of about 12 to 45 years have at least recorded PCOS symptoms. In fact as we speak, PCOS is actually thought be among the leading causes of subfertility and some of the most common endocrine problems in women, as well.
Apparently the most common symptoms of the condition include anovulation, insulin resistance and excessive production of androgenic hormones. For anovulation, the patient experiences irregular menstruation and amenorrhea, all of which result into ovulation-related infertility. Then there’s insulin resistance, which apparently stifles obesity, high cholesterol levels and type 2-diabetes. Closing the list of symptoms is the hormonal imbalance, which generally causes hirsutism and acne.
Like already mentioned, there’s a lot of uncertainty on the exact cause of the condition. But strong evidences point it as a genetic disease. For instance, there’s the familial clustering, the heritability of endocrine, and lastly, the greater concordance in monozygotic twins as compared to dizygotic ones, all of which link the condition with genetic issues.
Blocked Fallopian tube
The fallopian tube connects the two ovaries in a woman’s reproductive system to the uterus. In human reproduction, this is the exact spot where male sperm cells meet the egg for fertilization.
However, there are a number of conditions that can actually block the fallopian tube, and thus prevent fertilization from taking place. In fact, for fertilization to take place, the fallopian tube must be free of any form of obstruction and adhesion; otherwise, the egg will be blocked somewhere in the fallopian tube before it reaches the uterus.
Causes of blocked fallopian tube
The only practical implication of blocked fallopian tubes is decreased fertility, or lack thereof. And if one of the two fallopian tubes remains unblocked, then pregnancy is still very possible… yet blocked fallopian tubes have been marked as the major causes of infertility in women.
In some cases, when the tube is partially blocked, the sperm may find a way to reach the released egg. And if it happens to fertilize it, the fertilized egg may certainly not be able to reach the uterus to complete the transition, resulting into an ectopic pregnancy.